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Mastering Polynucleotides since 1952

The power of regeneration unlocked by a relentless passion for science and innovation

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Mastelli World

The Mastelli dermocosmetic portfolio combines scientific innovation with cosmetic efficacy, offering a complete line of products designed to meet the needs of all skin types, including the more sensitive ones. Thanks to the synergy of nucleotides, vitamins, and hyaluronic acid, Mastelli treatments promote deep hydration, cellular renewal, and protection of the skin barrier. From cleansing to daily skincare, each product is developed to support skin health and beauty through a regenerative, gentle, and highly tolerable approach


Discover our dermocosmetic line

Plinestcare Crema Viso Giorno Spf20 03 3 4
Face

Plinest®CARE Day Face Cream SPF20

Moisturizing and revitalizing, it combats free radicals and skin aging, protects against UV rays (SPF 20), and reduces wrinkles while enhancing elasticity, firmness, and radiance. Maintains the skin's natural pH, is suitable for sensitive skin, and works well as a makeup base. Contains Nucleotides for skin renewal and DNA repair, Hyaluronic Acid for deep hydration, and Vitamin E for antioxidant protection. Enriched with Acetil Tetrapeptide-2, it boosts collagen and elastin, strengthening the dermis and preventing sagging.

Plinestcare Crema Viso Giorno 01 3 4 1
Face

Plinest®CARE Day Face Cream

Moisturizing and revitalizing, it combats free radicals and skin aging, reducing wrinkles and enhancing elasticity, firmness, and radiance. It maintains the skin's natural pH, is suitable for sensitive skin, and works well as a makeup base. Contains Nucleotides for skin renewal and DNA repair, Hyaluronic Acid for deep hydration, and Vitamin E for antioxidant protection. Enriched with Acetyl Tetrapeptide-2, it boosts collagen and elastin, strengthening the dermis and counteracting sagging.

Plinest Care Crema Viso Notte 800x766
Face

Plinest®CARE Night Face Cream

At night, it supports cell regeneration, collagen protection, and hydration, helping to reduce wrinkles. Contains Nucleotides for skin renewal, Hyaluronic Acid for deep hydration, and Vitamin E to fight free radicals. Enriched with Acetyl Hexapeptide-51 Amide, it aids DNA repair and delays skin aging

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Eye contour

Plinest®CARE Eye Gel Contour

An intensive revitalizing and anti-aging gel that hydrates and reduces puffiness and dark circles. Its light texture is enriched with high and low-molecular-weight hyaluronic acid for deep hydration, elasticity, and firmness. Nucleotides promote skin renewal, collagen production, and antioxidant protection, while a plant extract complex enhances microcirculation and refreshes the eye contour area.

Plinest Care Siero 800x766
Face

Plinest®CARE Serum

Plinest®CARE Serum is an ultra-light anti-aging treatment with natural nucleotides that stimulate skin renewal and collagen production. Hyaluronic acid deeply hydrates, Vitamin E protects against free radicals and Acetyl SH-Heptapeptide-1 strengthens the skin’s defense mechanisms. Its high concentration ensures a rapid and intensive effect.

Plinestcare Crema Corpo 07 3 4
Body

Plinest®CARE Body Cream

Plinest®CARE Body Cream is formulated with nucleotides from natural sources (fish), which support cell renewal and improve skin elasticity. Hyaluronic acid provides deep hydration, increasing skin firmness and tone. Vitamin E, with its antioxidant action, helps combat skin aging and damage caused by free radicals and sun exposure. Additionally, jojoba oil, rich in tocopherols, has emollient and elasticizing properties, helping to prevent dryness and skin laxity.

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Hair and eyebrows, Body, Face

Plinest®CARE Body Hair Face Oil

Plinest®CARE Body Hair Face Oil is a multipurpose dry oil for the body, hair and face with a delicate and pleasant fragrance. It can be applied year-round, both in winter and summer

Makeskin Beauty Crema Corpo Me Slp
Body
MakesKin Beauty Body Cream

MakesKin Beauty Body Cream, formulated to combat sagging skin and signs of aging, helps keep skin firm, toned and hydrated

Makeskin Beauty Repair Emulsion Me Slp
Face, Neck, Décolleté
MakesKin Beauty Repair Emulsion

MakesKin Beauty Repair Emulsion is formulated for daily use, including as a home treatment in cases of cosmetic surgery and medicine

Makeskin Regenerative Cream 1
Body
MaKesKin Regenerative Cream

Regenerative cream for improving scars and skin trophism

Turnover Derma Slr
Body
Turnover Dermatological Cream

Turnover Dermatological Cream with Nucleotides promotes re-epithelialization processes, combats damage from solar radiation, and irritants and promotes orthoderma. Promotes re-epithelialization and skin repair in cases of eczema, dermatitis, redness, diaper rash

Rosaderm 1
Face
Rosaderm Cream

Rosaderm is a cosmetic cream for daily treatment of couperose with Nucleotides, Bisabolol, Vitamin E, and Hyaluronic Acid

Amelan 2020 Scatola
Body
Amelan

Daily depigmenting treatment that minimizes blemishes and evens out the skin tone thanks to its composition

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