Skin Priming with PN HPT® optimally prepares the skin, enhancing its response to subsequent aesthetic treatments. The result? A more intense, faster, and longer-lasting effect.
Thanks to their skin-activating action, PN HPT® amplify the overall effectiveness of combined treatments, delivering visible benefits from the very first sessions.
Today, our PN HPT®-based medical devices, backed by over 70 years of biotechnological expertise, are trusted by healthcare professionals in more than 30 countries. The commitment of the Mastelli Research and Development laboratory, together with our close collaboration with the international scientific community, has enabled us to consolidate company know-how that is now supported by over 100 scientific publications
Derived from the DNA of trouts bred in freshwater for human consumption, our Polynucleotides undergo advanced, high-temperature purification to create an exceptionally pure product, guaranteeing high levels of safety and tolerability
Polynucleotides play an important role in tissue regeneration by filling the spaces between cells and serving as a supportive scaffold.
This scaffold not only offers structural support but also provides essential hydration to maintain tissue volume, thanks to the remarkable ability of Polynucleotides to attract and bind water molecules.
Their water-binding capacity also helps to lubricate and regulate the viscosity of synovial fluid—an effect that is especially beneficial in orthopedic applications.
Together, these functions enable polynucleotides to create a protective, hydrated microenvironment that closely mimics natural physiological conditions, fostering cell vitality and promoting tissue health
All Mastelli Class III medical devices are approved by the Italian Ministry of Health, manufactured according to certified Good Manufacturing and Distribution Practices, and bear the CE marking in compliance with European regulations.
Registered in numerous countries worldwide, our products meet the highest standards of quality, safety, and reliability.
Polynucleotides are the building blocks of life. They are naturally found in every tissue and ready to act whenever cells are damaged or under stress.
Our polynucleotides, derived from the DNA of trouts bred in freshwater for human consumption, undergo advanced, high-temperature purification to create an exceptionally pure product free from allergenic or pharmacologically active protein contaminants